CT perfusion (CTP) has become one of the mainstays of acute stroke imaging. Due to its short acquisition times and its wide availability, it can lead to an accurate diagnosis faster than magnetic resonance imaging (MRI). Even if both modalities were readily available on a 24/7 setting – which is unrealistic in most places – the longer scan time of MRI still results in a lengthier diagnostic decision-making process. In addition, MRI only allows a restricted access to the patient during the scan time. This paper summarizes the results of three recent studies that tested the diagnostic accuracy of CTP, in comparison to diffusion-weighted and perfusion MR imaging.