HomeNewsContrast-enhanced coronary CT angiography has emerged as the most reliable imaging modality for demonstrating the potential impact of allopurinol therapy on coronary plaque stabilization in patients with acute coronary syndrome

Contrast-enhanced coronary CT angiography has emerged as the most reliable imaging modality for demonstrating the potential impact of allopurinol therapy on coronary plaque stabilization in patients with acute coronary syndrome

    In a prospective, double-blind, placebo-controlled, randomized trial, coronary plaque analysis was carried out to investigate the potential plaque stabilization induced by allopurinol therapy. This analysis was performed on contrast-enhanced coronary CT angiography (CCTA) images in patients with acute coronary syndrome (ACS). The findings obtained through this noninvasive imaging method demonstrated that allopurinol does not improve atherosclerotic plaque stability or inflammation in this patient population.