HomeNewsAdjustment of contrast medium dose to body weight should be recommended for adequate hepatic enhancement >50 Hounsfield units in all contrast-enhanced CT scans, without an upper body weight threshold

Adjustment of contrast medium dose to body weight should be recommended for adequate hepatic enhancement >50 Hounsfield units in all contrast-enhanced CT scans, without an upper body weight threshold

    A recent retrospective analysis evaluated 400 patients, all with glomerular filtration >45mL/min, who underwent contrast-enhanced thoraco-abdominal CT. The amount of contrast medium (CM) was tailored to body weight, and the correlation between body weight and mean hepatic enhancement (MHE) was evaluated. The MHE was assessed by calculating the delta between the pre-contrast and post-contrast hepatic attenuation. After appropriate evaluation of kidney function, adjustment of CM dose to body weight, without an upper body weight limit, might be an appropriate way to diminish the dependence of MHE on body weight. Overall, the presence of hepatosteatosis is one of the most relevant limitations for the MHE.