In order to optimize image quality for the assessment of small-sized vessels below the knee, a recent study from European Radiology compared CT angiography of the lower extremities performed with separate reconstructions of each leg using a small field-of-view (FOV) versus standard reconstructions based on a large FOV covering both legs. The side-separated reconstructions of each leg obtained with a small FOV significantly improved the image quality and delineation of the vessel wall, particularly in the presence of vascular calcifications, proving to be a precise and non-invasive diagnostic tool.