HomeNewsDual-energy CT with various iodinated contrast agent protocols used to identify iodine concentration reference values for normal bowel wall in the different bowel segments

Dual-energy CT with various iodinated contrast agent protocols used to identify iodine concentration reference values for normal bowel wall in the different bowel segments

    This retrospective single-center study included the normal abdominal studies of 248 patients who underwent abdominal contrast-enhanced dual-energy CT (DECT) for a variety of indications. The iodine dose varied according to the DECT indication, with three increasing doses: 400 mgI/kg body weight, 500 mgI/kg, and 600 mgI/kg.
    Bowel wall iodine concentration changed according to the bowel segment and was dependent on the total iodine dose. In particular, it was highest in the stomach and gradually decreased from the stomach to the rectum. When normalized for the aorta, it was directly proportional to the iodine dose, whereas, when normalized for the upper abdomen organs, it was independent from the characteristics of the patients and contrast agent.