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MDCT: An efficacious approach for the diagnosis of vasculitis

Dear users,

The term vasculitis collectively refers to several forms of inflammatory vascular disease, from Behçet’s syndrome, polymyalgia rheumatica and Takayasu arteritis to Kawasaki disease, polyarteritis nodosa, Wegener’s granulomatosis and others. The differential diagnosis among these conditions is efficiently supported by contrast-enhanced MDCT. An overview of these pathologies is provided by Dr. Anzidei’s Focus on, while the selected e-book and recently published articles highlight the use of MDCT imaging in the diagnosis of vascular diseases. Two practical cases illustrate the best method for a differential diagnosis through the use of contrast-enhanced MDCT and offer the opportunity to discover the main characteristics of particular vasculitides. Finally, Prof. Saba’s review examines the role of MDCT in distinguishing areas of vulnerable plaque in the carotid arteries.

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The team




MDCT of vulnerable plaque in the carotid arteries
L. Saba

Over the last 15 years, histopathological studies have demonstrated that some carotid artery plaque features were associated with the risk of plaque rupture. These features may be studied with fast MDCT imaging, which allows looking beyond the lumen to identify areas of vulnerable plaque and to understand the features of this lesion.

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Singh S, Sharma D, Bhattad S, Phillip S. Recent advances in Kawasaki Disease - Proceedings of the 3rd Kawasaki Disease Summit, Chandigarh, 2014. Indian J Pediatr. 2015 Aug 30. [Epub ahead of print]

Soliman M, Laxer R, Manson D et al. Imaging of systemic vasculitis in childhood. Pediatr Radiol. 2015 Jul;45(8):1110-1125

Korn A, Bender B, Brodoefel H et al. Grading of carotid artery stenosis in the presence of extensive calcifications: dual-energy CT angiography in comparison with contrast-enhanced MR angiography. Clin Neuroradiol. 2015 Mar;25(1):33-40

Itami H, Tokunaga K, Okuma Y et al. Novel 3D-CT evaluation of carotid stent volume: greater chronological expansion of stents in patients with vulnerable plaques. Neuroradiology. 2013 Sep;55(9):1153-1160


Atlas of Emergency Radiology

Agarwala R. – Springer 2015

• Front Matter »  

• Vasculitis » 



Acute chest pain
Boy, 13 years old
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Arm and hand pain
Man, 65 years old
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