Dear readers,
CT-derived fractional flow reserve (CT-FFR) has recently gained significant attention for its diagnostic and prognostic value when added to coronary CT angiography in the assessment of the functional severity of coronary lesions. Nonetheless, several aspects are still debated, including the most reliable approaches and algorithms for CT-FFR calculation and its practical implementation in routine clinical workflows.
In the videopill included in this Newsletter, Professor Loewe offers a comprehensive overview of the role of noninvasive CT-FFR in evaluating coronary lesions and stenoses. He highlights its major advantages—particularly the ability to provide accurate physiological data for ischemia assessment—while also addressing current challenges, such as selecting the most appropriate calculation method and incorporating it effectively into clinical practice.
Among the featured scientific papers, the first investigates which computational analytic model can best support CT-FFR in the assessment of coronary artery disease. The second examines the diagnostic performance of CT-FFR in patients with type 2 diabetes mellitus and unstable angina.
Finally, the clinical case presented in this Newsletter demonstrates the practical utility of CT-FFR showing how it can enhance diagnostic accuracy of stenosis severity and guide patient management decisions.
We remind you that suggestions for topics to be covered in future issues of this newsletter are welcome. Please send your proposals to us at editorial@mdct.net.
From the MDCT.net team