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MDCT of abdominal pathology: difficult diagnoses and strategies for optimization

Dear users,

MDCT is considered the most efficacious and reliable technique for evaluating abdominal diseases characterized by nonspecific clinical signs and difficult radiological diagnosis.

Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms that arise in the smooth muscle of the gastrointestinal tract, most often in the stomach. The new Focus on, by Doctor Ciolina and Professor Laghi, reviews the value of contrast-enhanced MDCT in the detection and characterization of GISTs, and in the assessment of these patients’ prognosis and response to therapy. The accompanying clinical cases illustrate other abdominal diseases of difficult radiological diagnosis.

The use of iodinated contrast medium for MDCT of the gastrointestinal tract in particular conditions needs special attention: the review and the e-lecture proposed in this Newsletter examine some optimization strategies related to the administration of contrast medium and CT imaging.

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The team




Optimization of kVp and mAs in contrast and non-contrast CT examinations
JF. Paul

Lowering radiation exposure during CT examinations increases image noise, with the risk that image quality may be insufficient for diagnostic purposes. A trade-off is necessary between radiation dose reduction and image quality preservation. Some recent studies and new technical advances can help us choose the best combination of kVp–mAs pair. view »



Poveda A, del Muro XG, López-Guerrero JA et al. GEIS 2013 guidelines for gastrointestinal sarcomas (GIST). Cancer Chemother Pharmacol. 2014 Nov;74(5):883-898

Winant AJ, Vora A, Ginter PS et al. More than just metastases: a practical approach to solid mesenteric masses. Abdom Imaging. 2014 Jun;39(3):605-621

Han NY, Park BJ, Park SS et al. Modified fusion imaging combining CT gastrography and CT angiography: an initial experience of preoperative mapping prior to laparoscopic exogastric wedge resection of small (<3 cm) gastric submucosal lesions. Abdom Imaging. 2014 Apr;39(2):242-250




Acute abdominal pain
Woman, 64 years old
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