A recent study from Radiology evaluated the role of dual-phase dual-energy contrast-enhanced CT pulmonary angiography in assessing tumor perfusion in non-small cell lung cancers according to the degree of hypoxia. This imaging method based on CT demonstrated higher perfusion at the front between tumor edge and lung parenchyma in hypoxic tumors, providing a noninvasive approach for the study of the profile of tumor neovascularization and in vivo insight into the invading tumor front.